Alex gains the trust of Annie, a nervous patient with an 70 pound tumor, only to lose it all when he offends her later when she over hears him saying things about her tomour. Derek chooses Meredith to assist with an elderly Parkinson’s patient who could have surgery to cure his diesese, but Bailey disapproves of their relationship and is determined to make Meredith suffer, saying it’s just “For the sake of balance”. Tensions escalate between Burke and Shepherd.