Derek and Meredith attempt to be discreet about their relationship when they spent the night at Meredith’s place. However, their haggard appearances the morning after speak volumes to everyone, including Bailey who repeatedly warned Meredith about their relationship’s potential consequences. While this is all happening, George suspects that their anaesthesiologist may be drinking on the job but chooses not to say anything about it, Izzie handles a patient who won’t let his girlfriend go – literally, Cristina gets a case of the flu, and Alex deals with a former competitor who self-mutilates.